Exploring a Novel Therapy to Reduce Breast Cancer Risk in High-risk Individuals
Problem:
People with a high genetic risk of breast cancer often face tough choices like surgery (mastectomy) to lower their risk, which can significantly affect their quality of life, especially for young women.
Project:
This study will explore a new therapy using antisense oligonucleotides, which has been effective in treating other genetic disorders, to see if it can help prevent breast cancer by altering gene splicing.
Outcome:
If successful, this therapy could offer a new way to reduce cancer risk without the need for surgery.
Future:
The research aims to create new, effective treatments for people with a genetic risk of breast cancer, improving their options and quality of life.
Project Update:
To prevent breast cancer, surgery like mastectomy is effective but can seriously affect a person’s life, especially younger women. Researchers are exploring new treatments that could reduce cancer risk without surgery by changing specific genes. They’re making good progress with gene-editing technology and working with the University of Southampton on this.
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