Problem
People with a high genetic risk of breast cancer often face tough choices like surgery (mastectomy) to lower their risk, which can significantly affect their quality of life, especially for young women.
Project
This study will explore a new therapy using antisense oligonucleotides, which has been effective in treating other genetic disorders, to see if it can help prevent breast cancer by altering gene splicing.
Outcome
If successful, this therapy could offer a new way to reduce cancer risk without the need for surgery.
Future
The research aims to create new, effective treatments for people with a genetic risk of breast cancer, improving their options and quality of life.
Project Update
To prevent breast cancer, surgery like mastectomy is effective but can seriously affect a person’s life, especially younger women. Researchers are exploring new treatments that could reduce cancer risk without surgery by changing specific genes. They’re making good progress with gene-editing technology and working with the University of Southampton on this.
Keep reading
View all
Can Functional MRI of the Brain help us understand Brain Fog in Women with Breast Cancer?
Up to 70% of women with breast cancer experience cognitive difficulties, but scientists still don't fully understand why this happens. Without a clear understanding of the underlying cause, it is d...
Exploring Better Breast Imaging for Women in Aotearoa New Zealand
Mammograms save lives by finding breast cancer early. But they do not work equally well for everyone.For women with very dense breast tissue, cancer can be harder to see on a standard mammogram. Th...
From Evidence to Action: Expanding the ‘Not a One-Size-Fits-All’ Breast Cancer Screening Model for Aotearoa New Zealand.
Breast cancer screening in Aotearoa New Zealand does not benefit all women equally. Many cancers are still found outside the national screening programme, and Māori and Pacific women can face delay...
















