One piece at a time: Patient-derived explants for precision medicine in Aotearoa NZ
Dr. Emma Nolan is working on a project to create a better model for breast cancer research in New Zealand. She is using tissue samples from women with breast cancer to make patient-derived explants. These explants will be used to test new treatments for breast cancer, including immunotherapy. The goal is to create a model that better represents the breast cancer found in New Zealand and to help develop better treatments for patients. The project aims to create a collection of explants that will be useful for improving the drug development process and personalizing treatment for patients.
Keep reading
View all
From Evidence to Action: Expanding the ‘Not a One-Size-Fits-All’ Breast Cancer Screening Model for Aotearoa New Zealand.
Problem:Breast cancer screening in Aotearoa New Zealand does not benefit all women equally. Many cancers are still found outside the national screening programme, and Māori and Pacific women can fa...
Using Deep Learning And Digital Pathology To Intrinsically Subtype Breast Cancer
Problem:Traditional pathology uses microscopes to examine tissue slides, but this method can be slow and inconsistent, and not all patients can afford advanced molecular testing. Project:Digital pa...
“Shielding” Macrophages: Uncovering Immune-Mediated Chemoresistance in Triple-Negative Breast Cancer
ProblemTriple-negative breast cancer (TNBC) is one of the hardest types to treat and affects Māori and Pacific women more than others. Many patients with TNBC don’t fully respond to chemotherapy, a...
